Observation on the Use and Abuse of Mercury, and on the Precautions Necessary in Its Employment — Story, Setting & Ideas

OBSERVATIONS ON THE USE AND ABUSE OF MERCURY, AND ON THE PRECAUTIONS NECESSARY _IN ITS EMPLOYMENT_.

BY A. PHILIPS WILSON, M. D. Fellow of the Royal College of Physicians, and of the Royal Society of Edinburgh, &c.

Winchester. Printed and Sold by JAMES ROBBINS.

Sold also by Messrs. CADELL and DAVIES, Strand; MURRAY, Fleet-street; and CROSBY and Co. Stationer’s Court, Ludgate Hill, LONDON.

The following Observations are addressed to the Public, with a view, on the one hand, to do away certain erroneous prepositions respecting the effects of Mercury, which impede the necessary employment of it; and on the other, to call its attention to the impropriety of an indiscriminate use of this medicine, by which much harm is often done, and the medicine itself brought into disrepute. The best way to effect these purposes seems to be, to make the public acquainted with what is really to be apprehended from an improper use of mercury, and the circumstances in which its bad effects shew themselves; by which every one may be enabled to distinguish these effects from such as proceed from other causes, as well as be warned against a use of this medicine which has become too prevalent.

Physicians will agree, that we do not possess a more valuable medicine than mercury. Not to mention the diseases for the cure of which it was first introduced, which, without its aid, almost uniformly prove fatal, and in which it is almost uniformly successful, we may appeal for the truth of this observation to its effects in some of the most dangerous forms of scrophula, in dropsies of different kinds, in inflammations, particularly chronic inflammations, and induration and enlargement of the different viscera.[A]

[A] If we except worm cases, in which mercury probably acts on the worms themselves, the various diseases in which mercury is useful, may perhaps be reduced to the two heads of inflammation and glandular obstruction. I believe there is nothing more erroneous than the opinion, that mercury will occasionally succeed in almost all diseases. This opinion has led to its employment in improper cases, and tended consequently to bring it into discredit. I have never found it successful except in the diseases here alluded to.

For many years after its introduction into practice, it was confined to a few diseases. At length it occurred to physicians, that a remedy, which in these proved so efficacious, might produce similar effects in other cases; and such has been the success of the trial, that during the last twenty years mercury has been coming into general use, with a rapidity unequalled in the history of any other medicine. But the more we are assured of its value, the more cautious we ought to be in its employment; both because it is of the greater consequence to prevent any prepossession against it, and because we know that there is no active medicine which can safely be trifled with.

The prejudices which prevail against the use of mercury seem to arise from three sources; the nature of the complaints in which it was first employed; the uneasiness which even its salutary operation, when carried to a certain extent, necessarily occasions; and the bad consequences which sometimes attend an improper use of it. It is surprising, that the first of these causes should operate against its use; yet such is the confusion which naturally creeps into our ideas on subjects in which we are not habitually interested, that the prejudices of not a few originate from this cause. Of such a prejudice it is surely unnecessary to say any thing. The other objections to the use of mercury are of more weight.

Like all other medicines which increase the secretion by the skin, the use of mercury tends to debilitate, and render the body more susceptible of cold. When mercury does not encrease any other excretion, the debility it occasions seems to be proportioned to the degree in which it promotes perspiration; and medicines which promote perspiration in a greater degree produce more sudden debility. We see a degree of weakness produced by the operation of James’s powders, or of Dover’s powders, (opium and ipecacuanha), in a few days which a moderate course of mercury would not occasion in many weeks.

Such is the tendency of mercury to promote the secretion by the skin, that it often runs off in this way almost as fast as it is received into the system, particularly on its first being used; so that it is sometimes difficult to make a sufficient quantity be retained to produce its desired effect. Some of the good effects of mercury seem, in a great measure, to arise from this action of it, particularly its tendency to counteract the inflammatory disposition and to relieve actual inflammation.